
- addressing gaps and building systems
our
approach
We build systems that keep people well by turning prevention into policy and practice
Rypple supports both governments and businesses in transitioning toward
prevention. We help answer two core questions;
our health-ing products
why? telos answers this
We help you make the case for prevention
Why it matters: Leaders need clear, data-driven proof that prevention delivers value. Rypple’s TELOS provides exactly that.
Core Capabilities:
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Predictive Analytics: Forecasts disease burden and visualises impact before investing
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ROI Calculator: Quantifies savings, productivity gains, and social return
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Policy Simulator: Tests strategies for equity, cost, and sustainability; Applies local data for real-world precision
Health-ing is powerful: We help you prove it, and act on it.
We help you plan and deliver
How it works: ZENO empowers organizations to plan and optimize vaccine rollouts with agility, clarity, and speed.
Core Capabilities:
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Run multiple ‘what-if’ scenarios to anticipate challenges
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Detect bottlenecks weeks in advance to prevent delays
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Flexible integration with existing data systems, with a simple user interface
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Optimize vaccine distribution across regions and locations
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Plan capacity & open vaccination centers based on real demand forecasts
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Accurately predict demand by age group, risk, and geography
Zeno proved to be effective throughout Europe during the COVID-19 pandemic
how? zeno is the answer
how? uma is here for you
We power sustainable implementation.
Why it matters: Most prevention efforts don’t fail for lack of evidence; they fail in execution. We help you close that gap with our Data for Action Framework.
Core Capabilities:
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Monitoring, Evaluation & Learning (MEL): Tracks short- and long-term results to adapt strategies over time
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Ripple Effect Mapping (REM): Incorporates new insights quickly to refine implementation in real time
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Impact Trajectory Simulation: Models how your prevention efforts evolve and scale over time
From strategy to sustained impact. We help you deliver prevention that lasts.
our integrated solution; we are making health-ing happen
We engage governments, funders, and communities to prioritize resilient healthcare systems.
We co-design solutions with local partners, ensuring healthcare is practical and context-driven.
We refine successful models and expand them across regions for long-term sustainability.
Our tools are a connected system for lasting change:
We meet you where you are and help you scale prevention that works.

"by advocating for a paradigm shift to health, we are bringing an end to the critical tension between care and profit"
A systemic approach to eradicating chronic lifestyle disease
health technology assessment
Empowering HTA success beyond dossiers
Because we understand the economics of health-ing — we help start-ups navigate the full complexity of HTA, from early anticipation through to payer acceptance.
1
Anticipating HTA challenges early
Rypple enables start-ups to identify and address health technology assessment challenges early, ensuring proactive solutions and payer acceptance.
2
Co-creation of HTA strategies
Our teams of dedicated health-ing experts facilitate co-creation of HTA approaches, tailoring strategies to each product's unique needs for optimal outcomes.
3
Comprehensive support and engagement
Rypple supports dossier development, advanced modelling, and stakeholder engagement — all aligned with effective HTA strategies.
law
economics
ethics
biostatistics
epidemiology
medicine
HTA

rypple's actions are aligned with the global SDGs

1.2 By 2030, reduce at least by half the proportion of men, women, and children of all ages living in poverty in all its dimensions according to national definitions
3.4 By 2030, reduce by one-third premature mortality from non-communicable diseases through prevention and treatment and promote mental health and well-being
3.8 Achieve universal health coverage, including financial risk protection, access to quality essential healthcare services, and access to safe, effective, quality, and affordable essential medicines and vaccines for all
10.4 Adopt policies, especially fiscal, wage, and social protection policies, and progressively achieve greater equality




