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We love
 health-ing 

We are dedicated, passionate, and focused on a common goal.

Our  leadership team 

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Ushma Issar

  • Ushma Issar

Ushma Issar is the CEO & Founder of Rypple with a decade of global experience in the medical device industry, excelling in sales. However, discomfort grew as success correlated with illness. This realization spurred her to found Rypple in 2023, aiming to reshape healthcare incentives.

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Rutger De Mare

  • Rutger De Mare

Rutger de Mare is the Chief Technology Officer (CTO) of Rypple and the founder of Quo Mare. He has  10+ years of modeling expertise for the Dutch Government.

Our  heads of product 

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Marton Perlaki

  • Marton Perlaki

Marton is the Head of Telos, Rypple’s evidence-to-investment platform for translating scientific research and economic data into estimates of the health, societal, and economic value of preventive interventions. With a background in sustainability, impact investing, and development economics, he brings expertise in research, impact measurement, and economic modelling to help decision-makers invest more effectively in long-term health.

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Wim Kuijsten

  • Marton Perlaki

Wim is the Product Owner of Zeno, Rypple’s vaccine logistics platform. With a background in econometrics and over 15 years of experience in operations research and planning optimisation, he played a leading role in developing Zeno for the Dutch COVID-19 vaccination programme. Wim combines quantitative modelling with a pragmatic, user-focused approach to turn complex planning challenges into clear, actionable decisions.

Our  health-ing catalysts 

Varsha Pavithran

Public Health Professional

Varsha Pavithran

"Dr. Pavithran is a researcher with an MDS in Public Health from Rajiv Gandhi University of Health Sciences, focusing on affordable preventive health solutions. With expertise in Dental Public Health and Epidemiology, she contributes as an editorial board member and peer-reviewer for scientific journals"

Linda Mulunda

Public Health Professional

Linda Mulunda

"Linda is a public health expert specializing in health economics and inequalities. She uses healthcare policies to address the needs of specific populations and has experience with screening programs and minority representation. Linda promotes better health outcomes through evidence-based policies that ensure equitable healthcare delivery"

Lana Vujosevic

Health Economist

Lana Vujosevic

"Lana is a research-driven health economist passionate about harnessing quantitative methods to shape evidence-based policies. With a robust background in evaluating healthcare systems and a commitment to interdisciplinary research, she strives to drive global improvements in healthcare decision-making"

Nachiket Kondhalkar

Data Scientist

Nachiket Kondhalkar

"Nachiket is a data scientist and systems thinker with a background in Engineering and Policy Analysis. He holds an MSc from TU Delft and has worked on projects addressing transportation resilience, flood-risk prevention, and financial stability. Skilled in agent-based modeling and geospatial analysis, he combines technical expertise with a passion for taking on societal grand challenges"

Bethan Whaley

Researcher

Bethan Whaley

"Bethan is an insights strategist with 10+ years experience helping brands and organisations better connect with human and customer needs. She is a seasoned researcher across qualitative and quantitative methods, with industry experience in EMEA and APAC. She is passionate about public health and playing a part in creating better health incomes for society & individuals"

Khushboo Jagiasi

Researcher

Khushboo Jagiasi

"Khushboo is a service designer with background in medicine and global health. She combines to systems design and behavioral approaches for human-centered innovations. She has worked across clinical settings, health communications, advocacy, and community engagement. Her current focus is on designing accessible, prevention-driven policies and services through user research, stakeholder mapping, and implementation toolkits"

Ilona Osrajnik

Legal Consultant

Ilona Osrajnik

"Ilona is a driven young legal professional passionate about driving systemic change. She excels in crafting innovative policies and advocating for sustainable solutions. With experience in legal counseling, regulatory compliance, and policy development, Ilona is committed to promoting equal opportunities and empowering communities to thrive"

Sarah Gaudenzi

Legal Consultant

Sarah Gaudenzi

"Sarah is a driven young legal professional passionate about advancing human rights and transitional justice. With expertise in international law, victim representation, and advocacy work, she is dedicated to promoting justice and empowering communities through meaningful systemic change"

Jennifer Kronstain

Sales / Business Development

Jennifer Kronstain

"Jennifer is an entrepreneur and strategic communications expert driving brand transformation, shaping compelling narratives, and launching revenue-generating strategies. She founded and led KMG Worldwide Public Relations, and earned her bachelor’s degree in English from Syracuse University and served four years on its national alumni board of directors as communications chair to the executive committee"

Janice Prentice

Government Relations

Janice Prentice

"Janice is a management consultant with 20 years of experience across government, charity, and private sectors. She delivers impactful projects on equity and systemic change in public services. Janice champions inclusive cultures that drive positive transformation in every organization. Her dedication to social equity makes her a valuable asset in collaborative efforts"

Sanduni Wijesekera

Communications

Sanduni Wijesekera

"Sanduni has a background in biomedical research and data management. She has worked across international settings, supporting interdisciplinary teams. At Rypple, She develops strategic messaging, digital content, and stakeholder engagement. She combines her scientific expertise and communication skills to support evidence-based initiatives and social impact"

Praise Saint-John

Communications

Praise Saint-John

"Praise is a biomedical scientist, researcher and health innovation professional with a strong focus on strategic leadership at the intersection of infectious diseases, digital health, and global health systems. She has a track record of driving cross-sector collaboration, shaping high-impact initiatives, and translating scientific expertise into scalable, real-world solutions."

Our  advisory board 

Dr. Simon L Bacon

Dr. Simon L Bacon, PhD, FTOS, FCCS, FABMR

Professor Bacon is a renowned professor and behavioral scientist who develops interventions for high-risk behaviors at individual, industry, and policy levels. His acclaimed multidisciplinary research focuses on health behaviors to reduce chronic diseases.

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Dr. Simon L Bacon

Charles Mander

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Charles Mander, former CFO of NS International, Squad Mobility, Felyx, Axelera.ai and Lumiors and investor in many more impact start-ups/scale-ups, has years of experience in finance and fundraising which he is now using to help Rypple achieve its aims.

Lindsay Clerkx

Lindsay Clerkx

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Lindsay Clerkx is an experienced Human Resources Director with a huge track record in the medical device industry, demonstrating passion and proven success in organizational, team, and leadership development across multiple healthcare technology organizations.

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Brain Li Han Wong

Brian Li Han Wong

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Dr Wong is a global public health expert and entrepreneur who advises health-tech start-ups. Drawing on a wealth of experience from his work with WHO and other global health organizations/initiatives at various levels, he shapes policy and strengthens health systems to foster equitable and sustainable health outcomes for all.

Prof. Dr. Wim Groot

Prof. Dr. Wim Groot

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Prof. Dr. Wim Groot, a distinguished professor of Health Economics and Evidence Based Education at Maastricht University since 1998, has published over 300 papers, advised international organizations, and served on numerous prestigious boards while mentoring 34 PhD students.

Billy Amzal

Billy Amzal

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Billy Amzal is an experienced researcher, consultant, and entrepreneur with over 25 years in quantitative clinical research, AI in health, and public health. He has contributed to around 100 HTA and submissions, authored over 100, and advised agencies such as EMA, EFSA, WHO, and FDA. He holds a PhD in Bayesian Modeling, an MBA, and a mathematical engineer from École Polynique.

John Ganzi

John Ganzi

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John Ganzi, a renowned expert in climate and sustainability, has an extensive track record working with governments on system transformation. He helps organizations identify climate-related opportunities and risks through CCRMI's specialized educational programs across multiple continents.

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